Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
D920_02451Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. (79 aa)    
Predicted Functional Partners:
lexA
Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
  
 0.998
D920_02453
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.87.
       0.992
D920_02449
Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; KEGG: efc:EFAU004_01007 5.5e-128 N-acetylmuramoyl-L-alanine amidase; Psort location: CytoplasmicMembrane, score: 8.77.
  
  
 0.984
D920_02443
DnaD domain protein; KEGG: ssr:SALIVB_1214 1.6e-11 tpiA; triosephosphate isomerase K02086; Psort location: Cytoplasmic, score: 7.50.
     
 0.983
D920_00707
Hypothetical protein; KEGG: lki:LKI_01225 2.0e-20 LexA repressor K09976; Psort location: CytoplasmicMembrane, score: 9.55.
 
    0.979
glyS
KEGG: efu:HMPREF0351_11972 0. glyS; glycine--tRNA ligase beta subunit K01879; Psort location: Cytoplasmic, score: 9.97.
       0.967
glyQ
KEGG: efu:HMPREF0351_11973 3.6e-163 glyQ; glycine--tRNA ligase alpha subunit K01878; Psort location: Cytoplasmic, score: 9.97.
       0.967
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
       0.965
D920_02450
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
       0.962
D920_03107
FAD dependent oxidoreductase; KEGG: efl:EF62_2294 1.5e-198 glpO; glycerol-3-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
       0.949
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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