Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (170 aa)    
Predicted Functional Partners:
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.998
D920_02457
KEGG: efc:EFAU004_01014 1.2e-269 recJ; single-stranded-DNA-specific exonuclease RecJ K07462; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.998
D920_02570
Adenylosuccinate lyase; KEGG: ehr:EHR_12950 1.2e-219 adenylosuccinate lyase; Psort location: Cytoplasmic, score: 9.97.
  
 0.998
rnz
Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
  
    0.994
D920_02459
Hypothetical protein; KEGG: edi:EDI_048910 0.00014 intracellular protein transport protein USO1; Psort location: CytoplasmicMembrane, score: 9.55.
       0.993
D920_02460
KEGG: efc:EFAU004_01016 2.1e-105 short chain dehydrogenase/reductase family oxidoreductase K07124; Psort location: Cytoplasmic, score: 9.97; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
    0.993
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.992
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: efc:EFAU004_01105 5.2e-203 purH; bifunctional purine biosynthesis protein PurH K00602; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.991
D920_02462
Hypothetical protein.
       0.988
purK
Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
  
  
 0.985
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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