Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
addAATP-dependent nuclease subunit A; ATP-dependent DNA helicase. (1239 aa)    
Predicted Functional Partners:
rexB
Putative ATP-dependent nuclease subunit B; ATP-dependent DNA helicase; Belongs to the helicase family. AddB/RexB type 2 subfamily.
 
 
 0.999
pheT
KEGG: efu:HMPREF0351_11283 0. pheT3; phenylalanine--tRNA ligase beta subunit K01890; Psort location: Cytoplasmic, score: 9.97; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
     
 0.997
sbcD
Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
  
  
 0.996
D920_01967
Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50.
     
 0.996
D920_02486
Transcriptional regulator, HxlR family; Psort location: Cytoplasmic, score: 7.50.
     
 0.996
pheS
KEGG: efc:EFAU004_01039 4.6e-172 pheS; phenylalanyl-tRNA synthetase subunit alpha K01889; Psort location: Cytoplasmic, score: 10.00.
     
 0.995
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
   
 0.993
D920_01855
Exonuclease SbcCD, C subunit; KEGG: efu:HMPREF0351_12427 2.8e-259 sbcC; exodeoxyribonuclease SbcC K03546; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.992
recD2
Helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.
  
 
 0.990
D920_02032
Dinuclear metal center protein, YbgI family; KEGG: hip:CGSHiEE_02770 1.7e-14 seryl-tRNA synthetase; Psort location: Cytoplasmic, score: 7.50; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
 
     0.990
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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