| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| D920_00538 | D920_01377 | D920_00538 | D920_01377 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Putative Xaa-Pro dipeptidase; KEGG: efu:HMPREF0351_10775 6.8e-162 pepQ; M24B family Xaa-Pro dipeptidase K01262; Psort location: Cytoplasmic, score: 9.97. | 0.888 |
| D920_00538 | D920_01967 | D920_00538 | D920_01967 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50. | 0.860 |
| D920_00538 | D920_02531 | D920_00538 | D920_02531 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | KEGG: efc:EFAU004_01072 3.2e-139 DNA polymerase III subunit delta K02340; Psort location: CytoplasmicMembrane, score: 8.16. | 0.989 |
| D920_00538 | D920_02532 | D920_00538 | D920_02532 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Metallo-beta-lactamase domain protein; KEGG: zga:zobellia_1566 0.0040 metallohydrolase; Psort location: Cytoplasmic, score: 7.50. | 0.998 |
| D920_00538 | D920_02533 | D920_00538 | D920_02533 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | ComEC/Rec2-like protein; KEGG: apb:SAR116_0501 1.0e-06 DNA uptake protein ComEC K02238; Psort location: CytoplasmicMembrane, score: 10.00. | 0.998 |
| D920_00538 | D920_02534 | D920_00538 | D920_02534 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | KEGG: efu:HMPREF0351_11245 1.1e-74 comEB; competence protein ComEB K01493; Psort location: Cytoplasmic, score: 7.50. | 0.994 |
| D920_00538 | D920_02535 | D920_00538 | D920_02535 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | comEA protein; KEGG: has:Halsa_0780 3.1e-08 glycogen/starch synthase K00703; Psort location: CytoplasmicMembrane, score: 9.96. | 0.594 |
| D920_00538 | guaA | D920_00538 | D920_01115 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.999 |
| D920_00538 | polA | D920_00538 | D920_02019 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.989 |
| D920_00538 | ribA | D920_00538 | D920_00540 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.999 |
| D920_01377 | D920_00538 | D920_01377 | D920_00538 | Putative Xaa-Pro dipeptidase; KEGG: efu:HMPREF0351_10775 6.8e-162 pepQ; M24B family Xaa-Pro dipeptidase K01262; Psort location: Cytoplasmic, score: 9.97. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.888 |
| D920_01377 | D920_01967 | D920_01377 | D920_01967 | Putative Xaa-Pro dipeptidase; KEGG: efu:HMPREF0351_10775 6.8e-162 pepQ; M24B family Xaa-Pro dipeptidase K01262; Psort location: Cytoplasmic, score: 9.97. | Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50. | 0.998 |
| D920_01377 | D920_02531 | D920_01377 | D920_02531 | Putative Xaa-Pro dipeptidase; KEGG: efu:HMPREF0351_10775 6.8e-162 pepQ; M24B family Xaa-Pro dipeptidase K01262; Psort location: Cytoplasmic, score: 9.97. | KEGG: efc:EFAU004_01072 3.2e-139 DNA polymerase III subunit delta K02340; Psort location: CytoplasmicMembrane, score: 8.16. | 0.686 |
| D920_01377 | D920_02532 | D920_01377 | D920_02532 | Putative Xaa-Pro dipeptidase; KEGG: efu:HMPREF0351_10775 6.8e-162 pepQ; M24B family Xaa-Pro dipeptidase K01262; Psort location: Cytoplasmic, score: 9.97. | Metallo-beta-lactamase domain protein; KEGG: zga:zobellia_1566 0.0040 metallohydrolase; Psort location: Cytoplasmic, score: 7.50. | 0.631 |
| D920_01377 | D920_02533 | D920_01377 | D920_02533 | Putative Xaa-Pro dipeptidase; KEGG: efu:HMPREF0351_10775 6.8e-162 pepQ; M24B family Xaa-Pro dipeptidase K01262; Psort location: Cytoplasmic, score: 9.97. | ComEC/Rec2-like protein; KEGG: apb:SAR116_0501 1.0e-06 DNA uptake protein ComEC K02238; Psort location: CytoplasmicMembrane, score: 10.00. | 0.631 |
| D920_01377 | D920_02534 | D920_01377 | D920_02534 | Putative Xaa-Pro dipeptidase; KEGG: efu:HMPREF0351_10775 6.8e-162 pepQ; M24B family Xaa-Pro dipeptidase K01262; Psort location: Cytoplasmic, score: 9.97. | KEGG: efu:HMPREF0351_11245 1.1e-74 comEB; competence protein ComEB K01493; Psort location: Cytoplasmic, score: 7.50. | 0.996 |
| D920_01377 | D920_02535 | D920_01377 | D920_02535 | Putative Xaa-Pro dipeptidase; KEGG: efu:HMPREF0351_10775 6.8e-162 pepQ; M24B family Xaa-Pro dipeptidase K01262; Psort location: Cytoplasmic, score: 9.97. | comEA protein; KEGG: has:Halsa_0780 3.1e-08 glycogen/starch synthase K00703; Psort location: CytoplasmicMembrane, score: 9.96. | 0.593 |
| D920_01377 | guaA | D920_01377 | D920_01115 | Putative Xaa-Pro dipeptidase; KEGG: efu:HMPREF0351_10775 6.8e-162 pepQ; M24B family Xaa-Pro dipeptidase K01262; Psort location: Cytoplasmic, score: 9.97. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.883 |
| D920_01377 | polA | D920_01377 | D920_02019 | Putative Xaa-Pro dipeptidase; KEGG: efu:HMPREF0351_10775 6.8e-162 pepQ; M24B family Xaa-Pro dipeptidase K01262; Psort location: Cytoplasmic, score: 9.97. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.977 |
| D920_01377 | ribA | D920_01377 | D920_00540 | Putative Xaa-Pro dipeptidase; KEGG: efu:HMPREF0351_10775 6.8e-162 pepQ; M24B family Xaa-Pro dipeptidase K01262; Psort location: Cytoplasmic, score: 9.97. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.594 |