Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
D920_02546GTP-binding protein TypA; KEGG: efu:HMPREF0351_11231 0. tufA3; elongation factor EF1A K06207; Psort location: CytoplasmicMembrane, score: 8.78. (610 aa)    
Predicted Functional Partners:
D920_02547
Inositol monophosphatase family protein; KEGG: efu:HMPREF0351_11230 5.7e-87 suhB; inositol-phosphate phosphatase K01092; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.998
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.997
D920_02548
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0223 family.
       0.995
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.991
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.989
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
 
   
 0.988
D920_02544
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0358 family.
       0.986
infC
Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
  
 
 0.984
D920_01349
DivIVA domain protein; KEGG: pyn:PNA2_0830 2.6e-05 V-type ATP synthase subunit H; K02121 V-type H+-transporting ATPase subunit E; Psort location: Cytoplasmic, score: 9.97.
     
 0.983
rimP
Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
  
  
 0.983
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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