Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
xptXanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (193 aa)    
Predicted Functional Partners:
D920_02570
Adenylosuccinate lyase; KEGG: ehr:EHR_12950 1.2e-219 adenylosuccinate lyase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.999
purK
Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
  
  
 0.999
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
  
 0.999
D920_02574
Xanthine permease; KEGG: apb:SAR116_1372 3.1e-70 xanthine/uracil permease K03458; Psort location: CytoplasmicMembrane, score: 10.00.
  
 0.999
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.998
guaC
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
  
  
 0.995
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.994
D920_02583
Hypothetical protein; KEGG: efu:HMPREF0351_11193 9.8e-99 dihydrodipicolinate synthase/N-acetylneuraminate lyase.
     
 0.993
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: efc:EFAU004_01105 5.2e-203 purH; bifunctional purine biosynthesis protein PurH K00602; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.991
D920_02584
Exo-glucosaminidase LytG family protein; KEGG: efc:EFAU004_01126 2.3e-81 N-acetylmuramoyl-L-alanine amidase; Psort location: Extracellular, score: 8.42.
     
 0.991
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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