Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_02583Hypothetical protein; KEGG: efu:HMPREF0351_11193 9.8e-99 dihydrodipicolinate synthase/N-acetylneuraminate lyase. (229 aa)    
Predicted Functional Partners:
D920_02584
Exo-glucosaminidase LytG family protein; KEGG: efc:EFAU004_01126 2.3e-81 N-acetylmuramoyl-L-alanine amidase; Psort location: Extracellular, score: 8.42.
       0.997
D920_02585
KEGG: efc:EFAU004_01127 3.8e-97 serine-type D-Ala-D-Ala carboxypeptidase; Psort location: CytoplasmicMembrane, score: 7.60.
       0.997
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
     
 0.993
D920_02574
Xanthine permease; KEGG: apb:SAR116_1372 3.1e-70 xanthine/uracil permease K03458; Psort location: CytoplasmicMembrane, score: 10.00.
       0.991
D920_02570
Adenylosuccinate lyase; KEGG: ehr:EHR_12950 1.2e-219 adenylosuccinate lyase; Psort location: Cytoplasmic, score: 9.97.
     
 0.988
purK
Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
       0.988
D920_02586
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.988
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
    0.985
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.984
D920_02779
hydroxymethylglutaryl-CoA reductase, degradative; KEGG: efu:HMPREF0351_11072 0. acetyl-CoA acetyltransferase K00054; Psort location: Cytoplasmic, score: 9.95.
  
  
 0.984
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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