Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_02672Toxin-antitoxin system, toxin component, RelE family. (73 aa)    
Predicted Functional Partners:
D920_00202
Addiction module antitoxin, RelB/DinJ family; Psort location: Cytoplasmic, score: 7.50.
   
   0.977
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
    0.962
D920_02727
Prevent-host-death family protein; KEGG: tgr:Tgr7_1341 0.0038 CheA signal transduction histidine kinase; K03407 two-component system, chemotaxis family, sensor kinase CheA; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.924
D920_02933
Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
     
 0.905
D920_01929
Nucleotidyltransferase domain protein; KEGG: gfo:GFO_1722 2.2e-07 nucleotidyltransferase K07075.
       0.900
D920_02353
KEGG: llk:LLKF_2194 3.0e-10 yuiD; GNAT family acetyltransferase; Psort location: Cytoplasmic, score: 7.50.
       0.873
D920_01313
Methyltransferase domain protein; KEGG: efu:HMPREF0351_10904 4.1e-203 methyltransferase; Psort location: Cytoplasmic, score: 7.50.
 
     0.866
D920_00018
Addiction module toxin, RelE/StbE family; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.840
D920_00418
N-6 DNA Methylase; KEGG: smn:SMA_1208 6.8e-59 hsdM; type I restriction-modification system, DNA-methyltransferase subunit M; K03427 type I restriction enzyme M protein; Psort location: Cytoplasmic, score: 7.50.
       0.837
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
       0.834
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
Server load: medium (50%) [HD]