Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
D920_02692ASCH domain protein; KEGG: pfr:PFREUD_17030 1.2e-10 PPA0563; thioredoxin K06888; Psort location: Cytoplasmic, score: 7.50. (150 aa)    
Predicted Functional Partners:
D920_00176
KEGG: efc:EFAU004_02529 3.6e-140 Ser/Thr protein phosphatase family protein; Psort location: Cytoplasmic, score: 7.50.
       0.991
D920_00177
Hypothetical protein; KEGG: lru:HMPREF0538_20279 1.0e-54 ppx3; exopolyphosphatase; Psort location: CytoplasmicMembrane, score: 8.16.
       0.991
D920_00178
HDIG domain protein; KEGG: efc:EFAU004_02527 2.9e-154 3'-5' exoribonuclease yhaM K03698; Psort location: Cytoplasmic, score: 7.50.
       0.991
pheT
KEGG: efu:HMPREF0351_11283 0. pheT3; phenylalanine--tRNA ligase beta subunit K01890; Psort location: Cytoplasmic, score: 9.97; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
       0.981
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
       0.973
D920_01003
Hypothetical protein; KEGG: efu:HMPREF0351_10125 4.5e-30 metG; methionine--tRNA ligase.
       0.967
glmU
UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
       0.967
mtnN
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
       0.967
D920_03086
Hydrolase, NUDIX family; KEGG: efu:HMPREF0351_10543 1.1e-76 nudF; ADP-ribose diphosphatase K01515; Psort location: Cytoplasmic, score: 7.50.
       0.967
D920_02693
KEGG: sgo:SGO_1241 6.6e-61 aminoglycoside adenylyltransferase; K05593 aminoglycoside 6-adenylyltransferase; Psort location: Cytoplasmic, score: 7.50.
 
     0.964
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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