Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_02722Copper-exporting ATPase; KEGG: efu:HMPREF0351_11881 5.2e-290 actP; P-ATPase superfamily P-type ATPase copper (Cu) transporter; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 10.00. (726 aa)    
Predicted Functional Partners:
D920_02721
Copper chaperone CopZ; KEGG: thl:TEH_11040 3.2e-11 copA; copper-transporting ATPase CopA K01533; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.999
D920_02720
Copper transport repressor, CopY/TcrY family; KEGG: bcz:BCZK0993 7.0e-18 blaI; beta-lactamase K07737; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.998
D920_01967
Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.993
D920_01594
Copper-exporting ATPase; KEGG: efc:EFAU004_01914 5.3e-297 copB; copper-translocating P-type ATPase; Psort location: CytoplasmicMembrane, score: 10.00.
 
    
0.992
D920_01592
Heavy metal-associated domain protein; KEGG: sif:Sinf_0238 8.4e-06 Copper chaperone.
  
 
 0.982
D920_02727
Prevent-host-death family protein; KEGG: tgr:Tgr7_1341 0.0038 CheA signal transduction histidine kinase; K03407 two-component system, chemotaxis family, sensor kinase CheA; Psort location: Cytoplasmic, score: 7.50.
     
 0.978
D920_01593
Copper-exporting ATPase; KEGG: efa:EF0298 0. copper-translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 10.00.
  
 
 0.972
D920_00538
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.971
D920_00720
HTH-type transcriptional repressor CzrA family protein; KEGG: apb:SAR116_2180 6.4e-08 ArsR family transcriptional regulator; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.971
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
     
 0.966
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
Server load: low (32%) [HD]