Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_02727Prevent-host-death family protein; KEGG: tgr:Tgr7_1341 0.0038 CheA signal transduction histidine kinase; K03407 two-component system, chemotaxis family, sensor kinase CheA; Psort location: Cytoplasmic, score: 7.50. (197 aa)    
Predicted Functional Partners:
D920_01594
Copper-exporting ATPase; KEGG: efc:EFAU004_01914 5.3e-297 copB; copper-translocating P-type ATPase; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.993
D920_02721
Copper chaperone CopZ; KEGG: thl:TEH_11040 3.2e-11 copA; copper-transporting ATPase CopA K01533; Psort location: Cytoplasmic, score: 9.97.
     
 0.993
D920_02720
Copper transport repressor, CopY/TcrY family; KEGG: bcz:BCZK0993 7.0e-18 blaI; beta-lactamase K07737; Psort location: Cytoplasmic, score: 7.50.
       0.991
D920_02726
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.984
D920_02722
Copper-exporting ATPase; KEGG: efu:HMPREF0351_11881 5.2e-290 actP; P-ATPase superfamily P-type ATPase copper (Cu) transporter; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.978
dinB
Putative DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
  
 0.976
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: efc:EFAU004_01105 5.2e-203 purH; bifunctional purine biosynthesis protein PurH K00602; Psort location: Cytoplasmic, score: 7.50.
       0.974
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
       0.972
purM
KEGG: efc:EFAU004_01107 3.1e-134 Phosphoribosylformylglycinamidine cyclo-ligase K01933; Psort location: Cytoplasmic, score: 9.97.
       0.972
D920_00018
Addiction module toxin, RelE/StbE family; Psort location: Cytoplasmic, score: 7.50.
 
 
 
 0.966
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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