Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
D920_02734Alkaline phosphatase synthesis transcriptional regulatory protein PhoP; KEGG: bbp:BBPR_1604 7.5e-53 two-component response regulator K07776; Psort location: Cytoplasmic, score: 9.97. (233 aa)    
Predicted Functional Partners:
D920_02733
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: efu:HMPREF0351_11844 6.7e-203 sensor histidine kinase K07636; Psort location: CytoplasmicMembrane, score: 8.78.
 
 
 0.999
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
     
 0.996
D920_02735
Hypothetical protein; KEGG: bay:RBAM_002200 3.2e-36 ybbK; hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
     
 0.995
D920_02736
Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
     
 0.995
D920_02299
Putative sensor protein kinase WalK; KEGG: efu:HMPREF0351_12361 1.2e-292 vicK; sensor histidine kinase VicK K07652; Psort location: CytoplasmicMembrane, score: 9.96.
 
 
 0.994
D920_01772
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: efc:EFAU004_00426 1.2e-114 sensor histidine kinase; Psort location: CytoplasmicMembrane, score: 8.78.
 
 0.991
D920_02067
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: efu:HMPREF0351_11400 1.7e-156 ciaH; sensor histidine kinase K14982; Psort location: CytoplasmicMembrane, score: 10.00.
 
 
 0.990
D920_03091
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: efc:EFAU004_00525 2.5e-141 sensor histidine kinase; Psort location: CytoplasmicMembrane, score: 9.99.
 
 
 0.985
D920_00799
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: efu:HMPREF0351_11008 2.1e-229 sensor histidine kinase; Psort location: CytoplasmicMembrane, score: 8.78.
 
 
 0.983
D920_00690
Phosphate transport system regulatory protein PhoU; Plays a role in the regulation of phosphate uptake.
  
  
 0.982
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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