Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
D920_02735Hypothetical protein; KEGG: bay:RBAM_002200 3.2e-36 ybbK; hypothetical protein; Psort location: Cytoplasmic, score: 7.50. (179 aa)    
Predicted Functional Partners:
D920_02736
Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
       0.997
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
       0.997
D920_02734
Alkaline phosphatase synthesis transcriptional regulatory protein PhoP; KEGG: bbp:BBPR_1604 7.5e-53 two-component response regulator K07776; Psort location: Cytoplasmic, score: 9.97.
     
 0.995
D920_02733
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: efu:HMPREF0351_11844 6.7e-203 sensor histidine kinase K07636; Psort location: CytoplasmicMembrane, score: 8.78.
 
     0.990
pheT
KEGG: efu:HMPREF0351_11283 0. pheT3; phenylalanine--tRNA ligase beta subunit K01890; Psort location: Cytoplasmic, score: 9.97; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
       0.979
purD
KEGG: efc:EFAU004_01104 3.4e-144 Phosphoribosylamine--glycine ligase K01945; Psort location: Cytoplasmic, score: 7.50; Belongs to the GARS family.
       0.967
purK
Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
       0.967
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
       0.967
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
       0.956
D920_02385
KEGG: efc:EFAU004_00891 3.1e-182 cyclopropane-fatty-acyl-phospholipid synthase K00574; Psort location: Cytoplasmic, score: 9.67.
     
 0.956
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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