| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| D920_00536 | D920_01143 | D920_00536 | D920_01143 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Putative toxin-antitoxin system, toxin component; KEGG: bme:BMEI1683 0.0018 zinc-dependent metallopeptidase K01417; Psort location: Cytoplasmic, score: 7.50. | 0.762 |
| D920_00536 | D920_01496 | D920_00536 | D920_01496 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.983 |
| D920_00536 | D920_01915 | D920_00536 | D920_01915 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Modification methylase HhaI family protein; KEGG: ssk:SSUD12_0445 3.9e-134 cytosine-specific methyltransferase; K00558 DNA (cytosine-5-)-methyltransferase. | 0.750 |
| D920_00536 | D920_01967 | D920_00536 | D920_01967 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50. | 0.990 |
| D920_00536 | D920_02075 | D920_00536 | D920_02075 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | 0.502 |
| D920_00536 | D920_02113 | D920_00536 | D920_02113 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | AMP-binding enzyme; KEGG: efu:HMPREF0351_11403 2.5e-203 acetate--CoA ligase; Psort location: Cytoplasmic, score: 7.50. | 0.688 |
| D920_00536 | D920_02641 | D920_00536 | D920_02641 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | RIP metalloprotease RseP; KEGG: efc:EFAU004_01722 1.5e-182 eep; membrane-associated zinc metalloprotease K11749; Psort location: CytoplasmicMembrane, score: 9.99. | 0.828 |
| D920_00536 | D920_02750 | D920_00536 | D920_02750 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | DNA-binding helix-turn-helix protein; Psort location: Cytoplasmic, score: 7.50. | 0.780 |
| D920_00536 | lysS | D920_00536 | D920_01495 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | lysine--tRNA ligase; KEGG: efc:EFAU004_02596 1.4e-248 lysS; lysyl-tRNA synthetase K04567; Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.963 |
| D920_01143 | D920_00536 | D920_01143 | D920_00536 | Putative toxin-antitoxin system, toxin component; KEGG: bme:BMEI1683 0.0018 zinc-dependent metallopeptidase K01417; Psort location: Cytoplasmic, score: 7.50. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.762 |
| D920_01143 | D920_01915 | D920_01143 | D920_01915 | Putative toxin-antitoxin system, toxin component; KEGG: bme:BMEI1683 0.0018 zinc-dependent metallopeptidase K01417; Psort location: Cytoplasmic, score: 7.50. | Modification methylase HhaI family protein; KEGG: ssk:SSUD12_0445 3.9e-134 cytosine-specific methyltransferase; K00558 DNA (cytosine-5-)-methyltransferase. | 0.565 |
| D920_01143 | D920_01967 | D920_01143 | D920_01967 | Putative toxin-antitoxin system, toxin component; KEGG: bme:BMEI1683 0.0018 zinc-dependent metallopeptidase K01417; Psort location: Cytoplasmic, score: 7.50. | Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50. | 0.920 |
| D920_01143 | D920_02750 | D920_01143 | D920_02750 | Putative toxin-antitoxin system, toxin component; KEGG: bme:BMEI1683 0.0018 zinc-dependent metallopeptidase K01417; Psort location: Cytoplasmic, score: 7.50. | DNA-binding helix-turn-helix protein; Psort location: Cytoplasmic, score: 7.50. | 0.843 |
| D920_01496 | D920_00536 | D920_01496 | D920_00536 | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.983 |
| D920_01496 | D920_01915 | D920_01496 | D920_01915 | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Modification methylase HhaI family protein; KEGG: ssk:SSUD12_0445 3.9e-134 cytosine-specific methyltransferase; K00558 DNA (cytosine-5-)-methyltransferase. | 0.726 |
| D920_01496 | D920_01967 | D920_01496 | D920_01967 | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50. | 0.980 |
| D920_01496 | D920_02075 | D920_01496 | D920_02075 | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | 0.574 |
| D920_01496 | D920_02113 | D920_01496 | D920_02113 | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | AMP-binding enzyme; KEGG: efu:HMPREF0351_11403 2.5e-203 acetate--CoA ligase; Psort location: Cytoplasmic, score: 7.50. | 0.871 |
| D920_01496 | D920_02641 | D920_01496 | D920_02641 | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | RIP metalloprotease RseP; KEGG: efc:EFAU004_01722 1.5e-182 eep; membrane-associated zinc metalloprotease K11749; Psort location: CytoplasmicMembrane, score: 9.99. | 0.427 |
| D920_01496 | D920_02750 | D920_01496 | D920_02750 | TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | DNA-binding helix-turn-helix protein; Psort location: Cytoplasmic, score: 7.50. | 0.850 |