Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_02778KEGG: efu:HMPREF0351_11071 6.6e-164 hydroxymethylglutaryl-CoA synthase K01641; Psort location: Cytoplasmic, score: 7.50. (397 aa)    
Predicted Functional Partners:
D920_00877
KEGG: efc:EFAU004_00259 6.4e-134 diphosphomevalonate decarboxylase K01597.
 
 
 0.999
D920_02779
hydroxymethylglutaryl-CoA reductase, degradative; KEGG: efu:HMPREF0351_11072 0. acetyl-CoA acetyltransferase K00054; Psort location: Cytoplasmic, score: 9.95.
 0.999
D920_00876
Mevalonate kinase; KEGG: efu:HMPREF0351_10225 7.4e-117 mvk; mevalonate kinase K00869; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.996
D920_00878
Phosphomevalonate kinase; KEGG: efc:EFAU004_00258 7.6e-163 phosphomevalonate kinase K00938; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.996
D920_01258
Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
  
 
 0.995
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.992
D920_02017
MaoC-like protein; KEGG: bcz:BCZK1747 2.8e-14 acyl dehydratase K01726; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.982
D920_01370
Geranyltranstransferase; KEGG: efu:HMPREF0351_10781 3.6e-101 ispA; geranyltranstransferase K13789; Psort location: Cytoplasmic, score: 9.95; Belongs to the FPP/GGPP synthase family.
  
 
 0.977
clpX
ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
  
  
 0.975
D920_02303
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.971
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.