Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_02782Toxin-antitoxin system, antitoxin component, HicB family; Psort location: Cytoplasmic, score: 7.50. (125 aa)    
Predicted Functional Partners:
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.979
pheT
KEGG: efu:HMPREF0351_11283 0. pheT3; phenylalanine--tRNA ligase beta subunit K01890; Psort location: Cytoplasmic, score: 9.97; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
       0.925
D920_00202
Addiction module antitoxin, RelB/DinJ family; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.875
D920_00203
Addiction module toxin, RelE/StbE family; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.874
D920_00155
Addiction module toxin, RelE/StbE family; KEGG: hip:CGSHiEE_07380 0.00026 glyS; glycyl-tRNA synthetase subunit beta K06218.
 
   
 0.861
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
     
 0.857
D920_01007
LrgA family protein; KEGG: btk:BT9727_3424 8.8e-11 holin-like protein K06518; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.856
D920_01117
DNA-binding helix-turn-helix protein; KEGG: mla:Mlab_1603 4.4e-12 adenine deaminase K01486; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.856
D920_00135
YD repeat protein; KEGG: phu:Phum_PHUM617500 0.0010 type II transmembrane protein, putative; Psort location: Cellwall, score: 9.20.
     
 0.855
D920_00018
Addiction module toxin, RelE/StbE family; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.850
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
Server load: low (18%) [HD]