Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
D920_02792e1-E2 ATPase; KEGG: efc:EFAU004_01228 0. cation transporter E1-E2 family ATPase; Psort location: CytoplasmicMembrane, score: 10.00. (776 aa)    
Predicted Functional Partners:
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
     
 0.960
D920_02317
Mg2+ transporter-C family protein; KEGG: hip:CGSHiEE_08975 1.2e-22 coaD; phosphopantetheine adenylyltransferase K07507; Psort location: CytoplasmicMembrane, score: 9.35.
  
 
 0.951
sigA
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
     
 0.950
D920_00178
HDIG domain protein; KEGG: efc:EFAU004_02527 2.9e-154 3'-5' exoribonuclease yhaM K03698; Psort location: Cytoplasmic, score: 7.50.
       0.940
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.936
D920_00176
KEGG: efc:EFAU004_02529 3.6e-140 Ser/Thr protein phosphatase family protein; Psort location: Cytoplasmic, score: 7.50.
   
 
 0.933
D920_00901
KEGG: efu:HMPREF0351_10204 0. aad; aldehyde-alcohol dehydrogenase K04072; Psort location: Cytoplasmic, score: 9.97; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.930
D920_01988
Chloride transporter, ClC family; KEGG: ssr:SALIVB_1179 3.8e-113 ribonuclease HII; Psort location: CytoplasmicMembrane, score: 10.00.
  
 
 0.929
D920_00177
Hypothetical protein; KEGG: lru:HMPREF0538_20279 1.0e-54 ppx3; exopolyphosphatase; Psort location: CytoplasmicMembrane, score: 8.16.
       0.914
mntH
Metal ion transporter, metal ion transporter family; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.
   
 0.913
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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