Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
D920_02831Putative Na+/H+ antiporter; KEGG: tgo:TGME49_105180 2.4e-17 sodium/hydrogen exchanger, putative; Psort location: CytoplasmicMembrane, score: 10.00. (695 aa)    
Predicted Functional Partners:
D920_02830
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.997
D920_02833
ABC transporter, ATP-binding protein; KEGG: efu:HMPREF0351_11121 5.6e-277 ABC superfamily ATP binding cassette transporter, ABC protein K15738; Psort location: Cytoplasmic, score: 9.95.
     
 0.997
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
     
 0.996
D920_02491
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.55.
       0.991
D920_01326
YihY family protein; KEGG: efu:HMPREF0351_10890 3.1e-118 rbn; ribonuclease BN K07058; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the UPF0761 family.
 
   
 0.987
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
       0.985
D920_01988
Chloride transporter, ClC family; KEGG: ssr:SALIVB_1179 3.8e-113 ribonuclease HII; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.984
D920_01197
Na+/H+ antiporter; KEGG: cnc:CNE_1c04080 8.6e-27 kdsD; arabinose 5-phosphate isomerase KdsD K03455; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
   
 
 0.981
D920_02619
KEGG: efc:EFAU004_01710 1.4e-131 ribF; riboflavin biosynthesis protein RibF K11753; Psort location: Cytoplasmic, score: 7.50.
     
 0.980
D920_02688
Penicillin-binding protein, transpeptidase domain protein; KEGG: efu:HMPREF0351_10994 0. pbp2B; penicillin-binding protein K00687; Psort location: CytoplasmicMembrane, score: 9.51.
     
 0.976
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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