Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_02836Channel protein, hemolysin III family; KEGG: lai:LAC30SC_04890 0.00066 tRNA CCA-pyrophosphorylase K00974; Psort location: CytoplasmicMembrane, score: 10.00. (217 aa)    
Predicted Functional Partners:
D920_02837
EDD domain protein, DegV family; KEGG: mgf:MGF_3873 5.6e-16 DegV-like protein; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.997
D920_02303
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.994
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.992
D920_02453
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.87.
       0.991
D920_02838
GDSL-like protein; KEGG: efc:EFAU004_01190 5.5e-121 GDSL-like lipase/acylhydrolase; Psort location: CytoplasmicMembrane, score: 9.55.
     
 0.984
D920_02840
Hypothetical protein.
       0.978
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
     
 0.977
smc
Segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
  
  
 0.975
D920_02842
Hypothetical protein; KEGG: lru:HMPREF0538_22032 2.9e-12 serine-type D-Ala-D-Ala carboxypeptidase; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0346 family.
       0.971
D920_02198
Putative methylated-DNA--[protein]-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
     
 0.970
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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