Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_02853Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. (228 aa)    
Predicted Functional Partners:
D920_01962
Hypothetical protein; Displays ATPase and GTPase activities.
     
 0.982
D920_01963
Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.
     
 0.982
whiA
Hypothetical protein; Involved in cell division and chromosome segregation.
     
 0.980
mprF
Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
 
     0.969
D920_00809
Hypothetical protein; KEGG: efc:EFAU004_01232 4.4e-286 ysyl-tRNA synthetase K14205; Psort location: CytoplasmicMembrane, score: 10.00.
 
     0.967
asnS
asparagine--tRNA ligase; KEGG: efc:EFAU004_01925 4.9e-223 asnS; asparaginyl-tRNA synthetase K01893; Psort location: Cytoplasmic, score: 10.00.
     
 0.965
D920_01540
ABC transporter, substrate-binding protein; KEGG: saj:SaurJH9_2430 1.2e-38 ribulose-phosphate 3-epimerase K01783; Psort location: CytoplasmicMembrane, score: 8.78; Belongs to the bacterial solute-binding protein 9 family.
       0.918
D920_01593
Copper-exporting ATPase; KEGG: efa:EF0298 0. copper-translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.917
uppP
Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
       0.901
D920_03029
ABC transporter, ATP-binding protein; KEGG: efu:HMPREF0351_12250 1.9e-180 msmK; maltose ABC superfamily ATP binding cassette transporter, ABC protein K10112; Psort location: CytoplasmicMembrane, score: 9.96.
       0.900
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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