Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ppaCInorganic diphosphatase PpaC; KEGG: efc:EFAU004_01167 6.2e-129 ppaC; manganese-dependent inorganic pyrophosphatase K15986; Psort location: Cytoplasmic, score: 9.97. (322 aa)    
Predicted Functional Partners:
D920_02870
KEGG: efc:EFAU004_01169 0. formate acetyltransferase K00656; Psort location: Cytoplasmic, score: 9.97.
     
 0.998
D920_02873
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
     
 0.995
parE
DNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily.
   
 
 0.994
D920_02871
Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
       0.994
parC
DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
  
    0.992
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.983
plsY
Acyl-phosphate glycerol 3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
 
     0.980
D920_02867
CoA binding domain protein; KEGG: rpm:RSPPHO_02409 3.4e-24 O-acetylhomoserine/O-acetylserine sulfhydrylase K01740; Psort location: Cytoplasmic, score: 7.50.
       0.976
D920_00641
KEGG: efc:EFAU004_02068 7.5e-37 GNAT family acetyltransferase K06975; Psort location: Cytoplasmic, score: 7.50.
  
    0.965
D920_01872
Methyltransferase small domain protein; KEGG: efu:HMPREF0351_12430 1.2e-98 methyltransferase; Psort location: Cytoplasmic, score: 7.50.
       0.964
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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