Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_02880Zinc-binding alcohol dehydrogenase family protein; KEGG: efu:HMPREF0351_12637 8.1e-111 NADPH:quinone reductase related Zn-dependent oxidoreductase; Psort location: Cytoplasmic, score: 9.67; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. (342 aa)    
Predicted Functional Partners:
clpB
ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
  
 0.986
D920_01967
Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.975
D920_02879
Hypothetical protein.
       0.972
menE
O-succinylbenzoate-CoA ligase; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
  
 
 0.954
D920_02776
Hypothetical protein; KEGG: efu:HMPREF0351_11070 2.1e-55 S-adenosyl-L-methionine methyltransferase; Psort location: Cytoplasmic, score: 7.50.
     
 0.953
D920_02613
KEGG: efi:OG1RF_10412 2.1e-158 ABC superfamily ATP binding cassette transporter, membrane protein K05845:K05846; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.946
D920_02725
ATPase family protein; KEGG: efu:HMPREF0351_11876 6.8e-107 AAA ATPase; K03924 MoxR-like ATPase; Psort location: Cytoplasmic, score: 9.97.
       0.943
D920_02128
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.938
D920_01579
Nitroreductase family protein; KEGG: efu:HMPREF0351_12619 1.3e-89 NADH dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.936
D920_02724
Hypothetical protein.
       0.932
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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