Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
D920_02933Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system. (59 aa)    
Predicted Functional Partners:
D920_00018
Addiction module toxin, RelE/StbE family; Psort location: Cytoplasmic, score: 7.50.
   
 
 0.954
D920_00155
Addiction module toxin, RelE/StbE family; KEGG: hip:CGSHiEE_07380 0.00026 glyS; glycyl-tRNA synthetase subunit beta K06218.
   
 
 0.954
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
       0.912
clpP
ATP-dependent Clp endopeptidase, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
     
 0.911
D920_02672
Toxin-antitoxin system, toxin component, RelE family.
     
 0.905
D920_00030
Death-on-curing family protein; KEGG: pdn:HMPREF9137_0457 1.0e-05 purC_2; phosphoribosylaminoimidazole succinocarboxamide synthase.
 
   
 0.901
D920_00203
Addiction module toxin, RelE/StbE family; Psort location: Cytoplasmic, score: 7.50.
     
 0.899
D920_01593
Copper-exporting ATPase; KEGG: efa:EF0298 0. copper-translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.843
D920_00418
N-6 DNA Methylase; KEGG: smn:SMA_1208 6.8e-59 hsdM; type I restriction-modification system, DNA-methyltransferase subunit M; K03427 type I restriction enzyme M protein; Psort location: Cytoplasmic, score: 7.50.
       0.842
ychF
GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
       0.840
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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