Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
D920_02942Fibronectin-binding protein; Psort location: Cytoplasmic, score: 7.50. (215 aa)    
Predicted Functional Partners:
D920_02941
Chloride transporter, ClC family; KEGG: cpr:CPR_1400 4.8e-19 chloride channel protein K01529; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.945
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.936
D920_02944
HD domain protein; KEGG: ova:OBV_05350 0.0085 2',3'-cyclic-nucleotide 2'-phosphodiesterase K06950; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.932
glmU
UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
     
 0.895
D920_01770
KEGG: efc:EFAU004_00424 0. ABC transporter ATP-binding protein/permease; Psort location: CytoplasmicMembrane, score: 10.00.
   
 
 0.881
D920_00456
Transcriptional regulator, effector binding domain protein.
 
   
 0.879
D920_00015
Topology modulation domain protein.
 
  
 0.844
rlmN
23S rRNA methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
  
  
 0.843
nrdR
Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
     
 0.837
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.833
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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