Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
D920_02983TIGR01906 family protein; Psort location: CytoplasmicMembrane, score: 10.00. (212 aa)    
Predicted Functional Partners:
D920_02984
HAD hydrolase family; KEGG: efu:HMPREF0351_12211 1.9e-109 HAD superfamily hydrolase.
  
    0.998
D920_02985
KEGG: fgr:FG10789.1 0.0055 hypothetical protein; K04799 flap endonuclease-1.
       0.997
D920_02986
KEGG: efc:EFAU004_02230 2.8e-195 Ser/Thr protein phosphatase family protein; Psort location: Cellwall, score: 8.97; Belongs to the 5'-nucleotidase family.
       0.996
D920_02198
Putative methylated-DNA--[protein]-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
       0.991
D920_00465
Nucleoside diphosphate kinase; KEGG: efu:HMPREF0351_10641 1.6e-50 ndk; nucleoside-diphosphate kinase K00940; Psort location: Cytoplasmic, score: 9.97; Belongs to the NDK family.
     
 0.981
D920_00698
Hypothetical protein.
 
     0.977
D920_02303
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.973
D920_02302
EDD domain protein, DegV family; KEGG: mgf:MGF_3873 1.2e-20 DegV-like protein; Psort location: Cytoplasmic, score: 7.50.
  
    0.971
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
 
     0.970
D920_01950
Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.967
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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