Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_02995DHHA1 domain protein; KEGG: efu:HMPREF0351_12223 1.8e-131 phosphoesterase K06881; Psort location: Cytoplasmic, score: 7.50. (321 aa)    
Predicted Functional Partners:
D920_02996
DRTGG domain protein; KEGG: bya:BANAU_2851 1.1e-108 ytoI; Inosine-5'-monophosphate dehydrogenase IMP dehydrogenase; Psort location: Cytoplasmic, score: 7.50.
     
 0.998
D920_02997
Metallo-beta-lactamase domain protein; KEGG: bqy:MUS_3211 3.9e-63 ytkL; metal dependent hydrolase; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0173 family.
     
 0.998
D920_01967
Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50.
       0.994
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.994
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
  
  
 0.993
D920_02998
Drug resistance MFS transporter, drug:H+ antiporter-2 family; KEGG: tpr:Tpau_0550 2.4e-44 tRNA-guanine transglycosylase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the major facilitator superfamily.
     
 0.993
cinA
Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.5e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Belongs to the CinA family.
     
 0.991
alaS
alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
 
  
 0.987
D920_01522
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.986
rny
YmdA/YtgF family protein; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
 
   
 0.986
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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