Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_03008CAAX amino terminal protease family protein; Psort location: CytoplasmicMembrane, score: 10.00. (259 aa)    
Predicted Functional Partners:
D920_01579
Nitroreductase family protein; KEGG: efu:HMPREF0351_12619 1.3e-89 NADH dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.955
cinA
Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.5e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Belongs to the CinA family.
       0.919
D920_01313
Methyltransferase domain protein; KEGG: efu:HMPREF0351_10904 4.1e-203 methyltransferase; Psort location: Cytoplasmic, score: 7.50.
     
 0.889
D920_02532
Metallo-beta-lactamase domain protein; KEGG: zga:zobellia_1566 0.0040 metallohydrolase; Psort location: Cytoplasmic, score: 7.50.
       0.879
D920_02533
ComEC/Rec2-like protein; KEGG: apb:SAR116_0501 1.0e-06 DNA uptake protein ComEC K02238; Psort location: CytoplasmicMembrane, score: 10.00.
       0.879
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.874
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.855
D920_00770
KEGG: efc:EFAU004_01774 4.6e-243 glycerophosphodiester phosphodiesterase family protein K01126; Psort location: CytoplasmicMembrane, score: 10.00.
       0.852
D920_00809
Hypothetical protein; KEGG: efc:EFAU004_01232 4.4e-286 ysyl-tRNA synthetase K14205; Psort location: CytoplasmicMembrane, score: 10.00.
 
   
 0.844
D920_00956
Chorismate mutase; KEGG: efc:EFAU004_00196 1.2e-100 maltose O-acetyltransferase K00661; Psort location: Cytoplasmic, score: 9.67.
     
 0.831
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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