Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_03059Stage III sporulation protein E; KEGG: reh:H16_A1582 3.2e-113 h16_A1582; DNA translocase FtsK K03466; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the FtsK/SpoIIIE/SftA family. (822 aa)    
Predicted Functional Partners:
D920_03061
ABC transporter, substrate-binding protein, family 3; KEGG: ebe:B21_00871 2.3e-26 artJ; artJ, subunit of arginine ABC transporter K09996.
     
 0.994
D920_03062
Putative glutamine ABC transporter, ATP-binding protein GlnQ; KEGG: efu:HMPREF0351_12277 3.4e-89 amino acid ABC superfamily ATP binding cassette transporter, ABC protein; Psort location: CytoplasmicMembrane, score: 8.78.
       0.993
D920_03063
Arginine ABC transporter, permease protein ArtQ family protein; KEGG: rcm:A1E_00665 2.8e-30 sdhA; succinate dehydrogenase flavoprotein subunit K02029; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.993
D920_00447
KEGG: bcz:BCZK3111 3.5e-09 GntR family transcriptional regulator K00837; Psort location: Cytoplasmic, score: 7.50.
     
 0.992
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
  
  
 0.984
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
  
 0.982
D920_02367
Hypothetical protein; KEGG: ppu:PP_2945 0.0026 sensor histidine kinase/response regulator; K02482 two-component system, NtrC family, sensor kinase.
  
 
 0.982
D920_01520
KEGG: efc:EFAU004_02618 2.5e-242 serine/threonine-protein kinase K08884; Psort location: CytoplasmicMembrane, score: 8.78.
     
 0.981
rlmN
23S rRNA methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
  
  
 0.979
D920_02532
Metallo-beta-lactamase domain protein; KEGG: zga:zobellia_1566 0.0040 metallohydrolase; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.978
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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