Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_03081Hypothetical protein. (191 aa)    
Predicted Functional Partners:
prs-2
Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
       0.995
D920_03082
Putative neprilysin; KEGG: efc:EFAU004_00535 1.6e-272 Peptidase family M13 K07386; Psort location: Cytoplasmic, score: 9.97.
       0.993
D920_03079
KEGG: efc:EFAU004_00538 3.2e-155 Putative cysteine desulfurase K04487; Psort location: Cytoplasmic, score: 9.97.
       0.991
D920_03078
Hypothetical protein.
       0.989
D920_03083
Isochorismatase family protein; KEGG: efu:HMPREF0351_10546 1.3e-78 nicotinamidase/isochorismatase; Psort location: Cytoplasmic, score: 7.50.
       0.977
mtnN
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
       0.965
D920_03085
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.55.
       0.930
D920_01786
Isochorismatase family protein; KEGG: efu:HMPREF0351_10454 1.3e-46 entB; isochorismatase.
       0.883
D920_03086
Hydrolase, NUDIX family; KEGG: efu:HMPREF0351_10543 1.1e-76 nudF; ADP-ribose diphosphatase K01515; Psort location: Cytoplasmic, score: 7.50.
       0.867
D920_00436
Isochorismatase family protein; KEGG: pfr:PFREUD_18100 4.9e-65 isochorismatase hydrolase; Psort location: Cytoplasmic, score: 7.50.
       0.823
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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