Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_03098Transporter, major facilitator family protein; KEGG: crn:CAR_c22760 2.0e-45 multidrug resistance protein B; Psort location: CytoplasmicMembrane, score: 10.00. (459 aa)    
Predicted Functional Partners:
D920_02246
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.55.
 
  
 0.971
D920_02248
KEGG: pfe:PSF113_2023 0.0011 MerR family transcriptional regulator; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.936
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.931
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.926
D920_00561
Putative permease; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.922
zwf
Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
  
 0.917
D920_01967
Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50.
     
 0.912
D920_00562
TIGR03943 family protein; Psort location: CytoplasmicMembrane, score: 8.16.
       0.901
D920_02215
Transcriptional regulator, TetR family; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.855
D920_00538
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.854
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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