Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
D920_03118Transcriptional regulator, PadR family; KEGG: ase:ACPL_2208 3.2e-06 Coproporphyrinogen 3 oxidase, aerobic. (105 aa)    
Predicted Functional Partners:
D920_03117
Hypothetical protein; KEGG: ams:AMIS_5630 0.0070 nuoH2; putative NADH dehydrogenase I chain H; K00337 NADH-quinone oxidoreductase subunit H; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.999
guaC
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
       0.991
D920_03104
KEGG: efc:EFAU004_00496 3.4e-135 FAD dependent oxidoreductase.
     
 0.990
D920_00871
Pentapeptide repeat family protein; KEGG: dsa:Desal_0704 0.0038 adenylate cyclase K05851.
     
 0.965
D920_00730
DNA-binding helix-turn-helix protein; KEGG: sgg:SGGBAA2069_c10720 0.0057 transcriptional regulator.
 
  
 0.924
D920_02077
KEGG: efi:OG1RF_12271 7.5e-211 cdr; coA-disulfide reductase; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.908
D920_01774
Hypothetical protein; KEGG: psb:Psyr_2690 0.0012 glycosyl transferase family protein; K10012 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.903
D920_01182
Hypothetical protein; KEGG: mfs:MFS40622_1065 0.0074 DEAD/H associated domain protein; K03724 ATP-dependent helicase Lhr and Lhr-like helicase; Psort location: CytoplasmicMembrane, score: 9.55.
  
  
 0.873
D920_01770
KEGG: efc:EFAU004_00424 0. ABC transporter ATP-binding protein/permease; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.872
D920_03116
Flavodoxin-like protein; KEGG: efc:EFAU004_00485 1.6e-80 NAD(P)H dehydrogenase.
       0.864
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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