STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXI14818.1Coproporphyrinogen dehydrogenase HemZ; KEGG: cdc:CD196_2583 4.8e-145 coproporphyrinogen III oxidase; K02495 oxygen-independent coproporphyrinogen III oxidase; Psort location: Cytoplasmic, score: 9.97. (523 aa)    
Predicted Functional Partners:
KXI14819.1
Metallo-beta-lactamase domain protein; KEGG: tjr:TherJR_1208 7.7e-35 Hydroxyacylglutathione hydrolase K01069; Psort location: Cytoplasmic, score: 7.50.
       0.837
hisS
histidine--tRNA ligase; KEGG: cdg:CDBI1_13355 3.6e-179 histidyl-tRNA synthetase; K01892 histidyl-tRNA synthetase; Psort location: Cytoplasmic, score: 10.00.
       0.835
KXI14821.1
Putative GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
    0.825
dtd
D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.
       0.824
aspS
aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
       0.815
KXI11596.1
Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
 
0.801
KXI10909.1
Methyltransferase, MtaA/CmuA family; KEGG: cby:CLM_1727 3.5e-62 uroporphyrinogen decarboxylase family protein; K01599 uroporphyrinogen decarboxylase; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.763
csoR
Putative copper-sensing transcriptional repressor CsoR; Psort location: Cytoplasmic, score: 7.50.
       0.695
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
  
 0.667
KXI10912.1
Hypothetical protein; KEGG: cbf:CLI_1576 3.2e-22 methylcobalamin:coenzyme M methyltransferase; Psort location: Cytoplasmic, score: 7.50; Belongs to the uroporphyrinogen decarboxylase family.
  
 
 0.665
Your Current Organism:
Peptostreptococcus anaerobius
NCBI taxonomy Id: 1261
Other names: ATCC 27337, CCUG 7835, CIP 104411, DSM 2949, LMG 15865, LMG:15865, NCTC 11460, P. anaerobius, Streptococcus anaerob, Streptococcus anaerobius, VPI 4330
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