STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
thiDPhosphomethylpyrimidine kinase; KEGG: cst:CLOST_2010 4.4e-71 thiD; bifunctional hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase K00941. (276 aa)    
Predicted Functional Partners:
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 0.999
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
 
 
 0.998
KXI13009.1
Thiamine biosynthesis protein ThiS.
  
 
  0.873
KXI13005.1
Putative thiamine-phosphate diphosphorylase; KEGG: fnu:FN1752 4.3e-34 regulatory protein TENI; K00788 thiamine-phosphate pyrophosphorylase; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.870
pdxK
Putative pyridoxal kinase; KEGG: cdc:CD196_1217 8.2e-79 pyridoxine kinase; K00868 pyridoxine kinase; Belongs to the pyridoxine kinase family.
  
 
 0.822
thiG
Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
  
 0.808
pdxS
Pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
    
 0.763
KXI10625.1
KEGG: cdg:CDBI1_03645 5.0e-214 putative ATP-dependent RNA helicase; K05592 ATP-dependent RNA helicase DeaD; Psort location: Cytoplasmic, score: 9.97; Belongs to the DEAD box helicase family.
 
 
   0.716
KXI14432.1
KEGG: cdg:CDBI1_11280 5.4e-233 inosine 5-monophosphate dehydrogenase K00088; Psort location: Cytoplasmic, score: 7.50.
   
 
 0.655
KXI11269.1
KEGG: eha:Ethha_0637 4.5e-94 riboflavin biosynthesis protein RibD K11752; Psort location: Cytoplasmic, score: 7.50.
   
  
 0.572
Your Current Organism:
Peptostreptococcus anaerobius
NCBI taxonomy Id: 1261
Other names: ATCC 27337, CCUG 7835, CIP 104411, DSM 2949, LMG 15865, LMG:15865, NCTC 11460, P. anaerobius, Streptococcus anaerob, Streptococcus anaerobius, VPI 4330
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