node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KXI14051.1 | aroE | HMPREF3195_00382 | HMPREF3195_01181 | Hydrolase, HD family; KEGG: bqy:MUS_2859 6.4e-31 nadD; putative nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate dehydrogenase family. | 0.545 |
KXI14051.1 | cinA | HMPREF3195_00382 | HMPREF3195_01548 | Hydrolase, HD family; KEGG: bqy:MUS_2859 6.4e-31 nadD; putative nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.6e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 7.50; Belongs to the CinA family. | 0.905 |
KXI14051.1 | kfoC_1 | HMPREF3195_00382 | HMPREF3195_00380 | Hydrolase, HD family; KEGG: bqy:MUS_2859 6.4e-31 nadD; putative nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Glycosyltransferase, group 2 family protein; KEGG: bce:BC5267 1.4e-37 glycosyltransferase K00754; Psort location: CytoplasmicMembrane, score: 9.51. | 0.545 |
KXI14051.1 | mrnC | HMPREF3195_00382 | HMPREF3195_00959 | Hydrolase, HD family; KEGG: bqy:MUS_2859 6.4e-31 nadD; putative nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | RNase3 domain protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | 0.544 |
KXI14051.1 | nadD | HMPREF3195_00382 | HMPREF3195_00383 | Hydrolase, HD family; KEGG: bqy:MUS_2859 6.4e-31 nadD; putative nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.997 |
KXI14051.1 | nadK | HMPREF3195_00382 | HMPREF3195_00417 | Hydrolase, HD family; KEGG: bqy:MUS_2859 6.4e-31 nadD; putative nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.720 |
KXI14051.1 | pncB2 | HMPREF3195_00382 | HMPREF3195_00511 | Hydrolase, HD family; KEGG: bqy:MUS_2859 6.4e-31 nadD; putative nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.780 |
KXI14051.1 | polC | HMPREF3195_00382 | HMPREF3195_01319 | Hydrolase, HD family; KEGG: bqy:MUS_2859 6.4e-31 nadD; putative nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | DNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.645 |
KXI14051.1 | rsfS | HMPREF3195_00382 | HMPREF3195_00381 | Hydrolase, HD family; KEGG: bqy:MUS_2859 6.4e-31 nadD; putative nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.902 |
KXI14051.1 | yhbY | HMPREF3195_00382 | HMPREF3195_00590 | Hydrolase, HD family; KEGG: bqy:MUS_2859 6.4e-31 nadD; putative nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | RNA-binding protein, YhbY family; Psort location: Cytoplasmic, score: 7.50. | 0.603 |
aroE | KXI14051.1 | HMPREF3195_01181 | HMPREF3195_00382 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate dehydrogenase family. | Hydrolase, HD family; KEGG: bqy:MUS_2859 6.4e-31 nadD; putative nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.545 |
aroE | nadD | HMPREF3195_01181 | HMPREF3195_00383 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate dehydrogenase family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.721 |
aroE | nadK | HMPREF3195_01181 | HMPREF3195_00417 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate dehydrogenase family. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.679 |
aroE | rsfS | HMPREF3195_01181 | HMPREF3195_00381 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate dehydrogenase family. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.582 |
aroE | yhbY | HMPREF3195_01181 | HMPREF3195_00590 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate dehydrogenase family. | RNA-binding protein, YhbY family; Psort location: Cytoplasmic, score: 7.50. | 0.514 |
cinA | KXI14051.1 | HMPREF3195_01548 | HMPREF3195_00382 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.6e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 7.50; Belongs to the CinA family. | Hydrolase, HD family; KEGG: bqy:MUS_2859 6.4e-31 nadD; putative nicotinate-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.905 |
cinA | nadD | HMPREF3195_01548 | HMPREF3195_00383 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.6e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 7.50; Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.969 |
cinA | nadK | HMPREF3195_01548 | HMPREF3195_00417 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.6e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 7.50; Belongs to the CinA family. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.592 |
cinA | pncB2 | HMPREF3195_01548 | HMPREF3195_00511 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.6e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 7.50; Belongs to the CinA family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.962 |
cinA | rsfS | HMPREF3195_01548 | HMPREF3195_00381 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.6e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 7.50; Belongs to the CinA family. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.906 |