STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXI13801.1Exonuclease SbcCD, C subunit; KEGG: hor:Hore_04030 4.4e-96 Exodeoxyribonuclease I subunit C K03546; Psort location: Cytoplasmic, score: 9.97. (907 aa)    
Predicted Functional Partners:
sbcD
Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 0.999
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.992
addA
ATP-dependent nuclease subunit A; ATP-dependent DNA helicase.
 
  
 0.887
KXI13804.1
Putative ATP-dependent nuclease subunit B; ATP-dependent DNA helicase.
 
  
 0.867
KXI13221.1
D-proline reductase, PrdA proprotein; KEGG: cdc:CD196_3054 3.1e-95 hypothetical protein; K10795 D-proline reductase (dithiol) PrdD; Psort location: Cytoplasmic, score: 9.97.
   
  0.861
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.831
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 0.824
KXI14360.1
DNA topoisomerase; KEGG: cdl:CDR20291_2294 1.6e-270 DNA topoisomerase; K03169 DNA topoisomerase III; Psort location: Cytoplasmic, score: 9.67.
  
 0.777
KXI13806.1
KEGG: cdf:CD1038 6.2e-129 helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.726
KXI13807.1
Hypothetical protein; KEGG: pfh:PFHG_04236 0.00038 conserved hypothetical protein; K01477 allantoicase; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.721
Your Current Organism:
Peptostreptococcus anaerobius
NCBI taxonomy Id: 1261
Other names: ATCC 27337, CCUG 7835, CIP 104411, DSM 2949, LMG 15865, LMG:15865, NCTC 11460, P. anaerobius, Streptococcus anaerob, Streptococcus anaerobius, VPI 4330
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