STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (245 aa)    
Predicted Functional Partners:
rsmH
S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
      0.952
lspA
Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
 
   
 0.742
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
  
    0.732
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
  
    0.702
yidC
Membrane protein insertase, YidC/Oxa1 family; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.649
gpsA
Putative glycerol-3-phosphate dehydrogenase [NAD(P)+ ]; KEGG: cdf:CD2630 4.4e-103 glyC; glycerol-3-phosphate dehydrogenase K00057; Psort location: Cytoplasmic, score: 7.50; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
    0.593
KXI13565.1
Peptidase M16 inactive domain protein; KEGG: bst:GYO_2040 2.1e-64 insulinase, peptidase family M16; Psort location: Cytoplasmic, score: 7.50.
  
    0.589
hprK
HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...]
  
  
 0.570
KXI13566.1
Peptidase M16 inactive domain protein; KEGG: cst:CLOST_1904 1.5e-125 insulysin, peptidase family m16 (insulinase); Psort location: Cytoplasmic, score: 7.50.
  
    0.558
KXI13029.1
r3H domain protein; KEGG: sgg:SGGBAA2069_c20720 6.9e-13 jag; Jag family RNA-binding protein K06346; Psort location: Cytoplasmic, score: 7.50.
  
    0.513
Your Current Organism:
Peptostreptococcus anaerobius
NCBI taxonomy Id: 1261
Other names: ATCC 27337, CCUG 7835, CIP 104411, DSM 2949, LMG 15865, LMG:15865, NCTC 11460, P. anaerobius, Streptococcus anaerob, Streptococcus anaerobius, VPI 4330
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