STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sigBPutative RNA polymerase sigma-B factor; KEGG: amt:Amet_2694 1.2e-22 RNA polymerase sigma-28 subunit FliA/WhiG K02405; Psort location: Cytoplasmic, score: 9.97; Belongs to the sigma-70 factor family. (257 aa)    
Predicted Functional Partners:
KXI13017.1
KEGG: cdl:CDR20291_3551 9.9e-35 rsbW; anti-sigma-B factor (serine-protein kinase); K04757 anti-sigma B factor; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.996
KXI13018.1
KEGG: naz:Aazo_2518 0.00023 anti-sigma-factor antagonist and sugar transfersase.
 
 
 0.995
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.806
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.760
mscS
Transporter, small conductance mechanosensitive ion channel MscS family protein; KEGG: mla:Mlab_1701 2.8e-21 phosphoglycerate mutase K01834; Psort location: CytoplasmicMembrane, score: 10.00.
       0.757
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.701
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.697
recF
Putative DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.
       0.665
KXI13022.1
S4 domain protein; KEGG: pal:PAa_0782 0.0040 rsuA; 16S rRNA pseudouridylate synthase; K06178 23S rRNA pseudouridine2605 synthase.
       0.665
KXI13239.1
Stage II sporulation protein E; KEGG: lbi:LEPBI_I1575 6.2e-23 putative phosphodiesterase or phosphatase K07315.
 
 
 0.643
Your Current Organism:
Peptostreptococcus anaerobius
NCBI taxonomy Id: 1261
Other names: ATCC 27337, CCUG 7835, CIP 104411, DSM 2949, LMG 15865, LMG:15865, NCTC 11460, P. anaerobius, Streptococcus anaerob, Streptococcus anaerobius, VPI 4330
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.