STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnpARibonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (129 aa)    
Predicted Functional Partners:
rpmH
Ribosomal protein L34; KEGG: rri:A1G_05155 1.0e-09 rpmH; 50S ribosomal protein L34 K02914; Psort location: Cytoplasmic, score: 9.67; Belongs to the bacterial ribosomal protein bL34 family.
  
  
 0.985
yidD
Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
  
  
 0.984
yidC
Membrane protein insertase, YidC/Oxa1 family; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.958
rex
Putative redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
   
    0.953
KXI13029.1
r3H domain protein; KEGG: sgg:SGGBAA2069_c20720 6.9e-13 jag; Jag family RNA-binding protein K06346; Psort location: Cytoplasmic, score: 7.50.
 
    0.860
rpsJ
Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
    0.802
rpsL
Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
    0.792
dnaA
Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
  
  
 0.780
rplD
50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.
   
  
 0.771
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
  
 0.747
Your Current Organism:
Peptostreptococcus anaerobius
NCBI taxonomy Id: 1261
Other names: ATCC 27337, CCUG 7835, CIP 104411, DSM 2949, LMG 15865, LMG:15865, NCTC 11460, P. anaerobius, Streptococcus anaerob, Streptococcus anaerobius, VPI 4330
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