STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mutLDNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (627 aa)    
Predicted Functional Partners:
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
 0.999
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 0.994
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.987
miaA
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
  
 0.959
KXI10849.1
Aluminum resistance protein; KEGG: bqy:MUS_1917 6.4e-111 ynbB; cystathionine gamma-lyase; Psort location: Cytoplasmic, score: 7.50.
       0.811
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 0.787
pcrA
KEGG: cdf:CD0328 4.8e-264 pcrA; ATP-dependent DNA helicase K03657; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.732
KXI10605.1
UvrD/REP helicase; KEGG: cdf:CD0749 1.4e-177 ATP-dependent DNA helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.712
KXI13806.1
KEGG: cdf:CD1038 6.2e-129 helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.704
KXI13807.1
Hypothetical protein; KEGG: pfh:PFHG_04236 0.00038 conserved hypothetical protein; K01477 allantoicase; Psort location: Cytoplasmic, score: 7.50.
   
 
 0.704
Your Current Organism:
Peptostreptococcus anaerobius
NCBI taxonomy Id: 1261
Other names: ATCC 27337, CCUG 7835, CIP 104411, DSM 2949, LMG 15865, LMG:15865, NCTC 11460, P. anaerobius, Streptococcus anaerob, Streptococcus anaerobius, VPI 4330
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