STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXI10646.1Hydrolase, NUDIX family; KEGG: aae:aq_158 7.6e-12 apfA; AP4A hydrolase; K03574 7,8-dihydro-8-oxoguanine triphosphatase. (140 aa)    
Predicted Functional Partners:
nnrE
YjeF domain protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
  
 0.973
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
   
  0.871
rnr
Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
   
 0.854
rph
tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
  
 
 0.850
KXI12467.1
Pyruvate kinase; KEGG: cdl:CDR20291_3216 3.2e-210 pykF; pyruvate kinase; K00873 pyruvate kinase; Psort location: Cytoplasmic, score: 7.50.
    
  0.797
KXI14261.1
DEAD-box ATP-dependent RNA helicase CshA family protein; KEGG: cbk:CLL_A1477 1.4e-97 cold-shock deAd box protein a; Psort location: Cytoplasmic, score: 9.97.
   
 0.785
KXI10625.1
KEGG: cdg:CDBI1_03645 5.0e-214 putative ATP-dependent RNA helicase; K05592 ATP-dependent RNA helicase DeaD; Psort location: Cytoplasmic, score: 9.97; Belongs to the DEAD box helicase family.
   
 0.785
KXI14432.1
KEGG: cdg:CDBI1_11280 5.4e-233 inosine 5-monophosphate dehydrogenase K00088; Psort location: Cytoplasmic, score: 7.50.
    
 0.771
cinA
Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.6e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 7.50; Belongs to the CinA family.
    
  0.748
KXI13050.1
DnaD domain protein; Psort location: Cytoplasmic, score: 7.50.
  
     0.723
Your Current Organism:
Peptostreptococcus anaerobius
NCBI taxonomy Id: 1261
Other names: ATCC 27337, CCUG 7835, CIP 104411, DSM 2949, LMG 15865, LMG:15865, NCTC 11460, P. anaerobius, Streptococcus anaerob, Streptococcus anaerobius, VPI 4330
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