STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucCsuccinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa)    
Predicted Functional Partners:
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
odhA
2-oxoglutarate dehydrogenase E1 component; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
 
 0.986
SFQ75102.1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.973
SFQ46241.1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.973
SFQ47247.1
Succinate dehydrogenase / fumarate reductase iron-sulfur subunit.
 
 0.971
SFQ47213.1
Succinate dehydrogenase subunit C.
 
 
 0.964
SFQ47229.1
Succinate dehydrogenase subunit A.
 
 0.945
SFQ05882.1
2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.925
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.920
SFQ74921.1
2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase).
 
 0.917
Your Current Organism:
Psychrobacillus psychrotolerans
NCBI taxonomy Id: 126156
Other names: Bacillus psychrotolerans, Bacillus psychrotolerans Abd El-Rahman et al. 2002, CIP 107792, DSM 11706, NCIMB 13838, P. psychrotolerans, Psychrobacillus psychrotolerans (Abd El-Rahman et al. 2002) Krishnamurthi et al. 2011, strain 3H1
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