STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
addBDNA helicase/exodeoxyribonuclease V, subunit B; ATP-dependent DNA helicase; Belongs to the helicase family. AddB/RexB type 1 subfamily. (1164 aa)    
Predicted Functional Partners:
addA
DNA helicase/exodeoxyribonuclease V, subunit A; ATP-dependent DNA helicase.
 
 0.999
SFM70094.1
DNA helicase-2 / ATP-dependent DNA helicase PcrA.
    
 0.878
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
     
 0.845
SFM35217.1
Uncharacterized protein.
       0.760
SFN03183.1
tRNA (adenine22-N1)-methyltransferase.
 
     0.667
SFM35236.1
2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).
       0.656
sbcD
Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
  
 0.576
SFN09504.1
Peroxiredoxin, Ohr subfamily.
   
    0.570
SFM35255.1
Protein of unknown function.
       0.537
SFN04463.1
single-stranded-DNA-specific exonuclease.
     
 0.508
Your Current Organism:
Psychrobacillus psychrodurans
NCBI taxonomy Id: 126157
Other names: ATCC BAA-796, Bacillus psychrodurans, Bacillus psychrodurans Abd El-Rahman et al. 2002, CIP 107791, DSM 11713, NCIMB 13837, P. psychrodurans, Psychrobacillus psychrodurans (Abd El-Rahman et al. 2002) Krishnamurthi et al. 2011, strain 68E3
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.