node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCX51856.1 | CCX52391.1 | BN689_01667 | BN689_00443 | Putative uncharacterized protein; Product inferred by homology to UniProt. | Putative uncharacterized protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.843 |
CCX51856.1 | ffh | BN689_01667 | BN689_00083 | Putative uncharacterized protein; Product inferred by homology to UniProt. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.904 |
CCX51856.1 | ftsY | BN689_01667 | BN689_01455 | Putative uncharacterized protein; Product inferred by homology to UniProt. | Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.905 |
CCX51856.1 | secA | BN689_01667 | BN689_01801 | Putative uncharacterized protein; Product inferred by homology to UniProt. | Protein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.835 |
CCX51856.1 | secD | BN689_01667 | BN689_01528 | Putative uncharacterized protein; Product inferred by homology to UniProt. | Putative uncharacterized protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.986 |
CCX51856.1 | secE | BN689_01667 | BN689_00565 | Putative uncharacterized protein; Product inferred by homology to UniProt. | Preprotein translocase SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.926 |
CCX51856.1 | secY | BN689_01667 | BN689_00475 | Putative uncharacterized protein; Product inferred by homology to UniProt. | Protein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.813 |
CCX51856.1 | yidC | BN689_01667 | BN689_00839 | Putative uncharacterized protein; Product inferred by homology to UniProt. | Membrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.923 |
CCX52080.1 | secA | BN689_00209 | BN689_01801 | Alkaline phosphatase family protein; Product inferred by homology to UniProt; Belongs to the alkaline phosphatase family. | Protein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.796 |
CCX52391.1 | CCX51856.1 | BN689_00443 | BN689_01667 | Putative uncharacterized protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Putative uncharacterized protein; Product inferred by homology to UniProt. | 0.843 |
CCX52391.1 | ffh | BN689_00443 | BN689_00083 | Putative uncharacterized protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.941 |
CCX52391.1 | ftsY | BN689_00443 | BN689_01455 | Putative uncharacterized protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.943 |
CCX52391.1 | rplW | BN689_00443 | BN689_00432 | Putative uncharacterized protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.677 |
CCX52391.1 | secA | BN689_00443 | BN689_01801 | Putative uncharacterized protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.983 |
CCX52391.1 | secD | BN689_00443 | BN689_01528 | Putative uncharacterized protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Putative uncharacterized protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.999 |
CCX52391.1 | secE | BN689_00443 | BN689_00565 | Putative uncharacterized protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.998 |
CCX52391.1 | secY | BN689_00443 | BN689_00475 | Putative uncharacterized protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.995 |
CCX52391.1 | yidC | BN689_00443 | BN689_00839 | Putative uncharacterized protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Membrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.982 |
ffh | CCX51856.1 | BN689_00083 | BN689_01667 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Putative uncharacterized protein; Product inferred by homology to UniProt. | 0.904 |
ffh | CCX52391.1 | BN689_00083 | BN689_00443 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Putative uncharacterized protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.941 |