STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metGmethionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (688 aa)    
Predicted Functional Partners:
pheS
phenylalanine--tRNA ligase alpha subunit; Product inferred by homology to UniProt; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
  
 0.994
leuS
leucine--tRNA ligase; Product inferred by homology to UniProt; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
0.992
pheT
phenylalanine--tRNA ligase beta subunit; Product inferred by homology to UniProt; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
 
 0.975
argS
arginine--tRNA ligase; Product inferred by homology to UniProt.
 
 0.962
asnS
asparagine--tRNA ligase; Product inferred by homology to UniProt.
  
 0.949
ileS
isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
 
 0.944
gltX
glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
  
 0.924
glnS
glutamine--tRNA ligase; Product inferred by homology to UniProt.
  
 0.924
guaA
gMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
  
 
 0.918
lysS
lysine--tRNA ligase; Product inferred by homology to UniProt; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 0.913
Your Current Organism:
Alistipes sp. CAG831
NCBI taxonomy Id: 1262698
Other names: A. sp. CAG:831, Alistipes sp. CAG:831
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