STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDE04172.1Heat shock protein Hsp20; Product inferred by homology to UniProt; Belongs to the small heat shock protein (HSP20) family. (145 aa)    
Predicted Functional Partners:
CDE04493.1
aTPase with chaperone activity ATP-binding subunit; Product inferred by homology to UniProt; Belongs to the ClpA/ClpB family.
  
 
 0.849
CDE06041.1
aTP-dependent Clp protease ATP-binding subunit ClpE; Product inferred by homology to UniProt; Belongs to the ClpA/ClpB family.
  
 
 0.849
CDE02921.1
Chaperone protein DnaJ; Product inferred by homology to UniProt.
  
 
 0.726
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.708
grpE
Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.695
CDE06823.1
Heat shock protein Hsp90; Product inferred by homology to UniProt.
  
 
 0.636
CDE03480.1
Serine/threonine protein kinase with PASTA sensor(S); Product inferred by homology to UniProt.
  
 
 0.571
rplP
50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
   
 
 0.540
CDE05414.1
Putative uncharacterized protein; Product inferred by homology to UniProt.
   
 
 0.508
lon
Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
  
  
 0.472
Your Current Organism:
Anaerotruncus sp. CAG390
NCBI taxonomy Id: 1262703
Other names: A. sp. CAG:390, Anaerotruncus sp. CAG:390
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