STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (125 aa)    
Predicted Functional Partners:
CCX54066.1
Glycine dehydrogenase subunit 2; Product inferred by homology to UniProt.
 
 0.999
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
 
 0.999
CCX54626.1
Dihydrolipoyl dehydrogenase; Product inferred by homology to UniProt.
 
  
 0.999
CCX56289.1
Lipoyltransferase and lipoate-protein ligase; Product inferred by homology to UniProt.
 
 
 0.994
CCX54068.1
Probable glycine dehydrogenase [decarboxylating] subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
 
 0.994
CCX55362.1
Serine hydroxymethyltransferase; Product inferred by homology to UniProt.
 
 
 0.973
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
     
 0.938
CCX56494.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
     
 0.932
CCX54913.1
Glutamate dehydrogenase; Product inferred by homology to UniProt; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
  0.871
CCX57305.1
Putative uncharacterized protein; Product inferred by homology to UniProt.
   
 0.769
Your Current Organism:
Bacteroides sp. CAG1060
NCBI taxonomy Id: 1262734
Other names: B. sp. CAG:1060, Bacteroides sp. CAG:1060
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