STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nfoProbable endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (280 aa)    
Predicted Functional Partners:
CDA22473.1
Glycosyl hydrolase family 43; Product inferred by homology to UniProt; Belongs to the glycosyl hydrolase 43 family.
       0.752
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
 
 0.677
CDA22721.1
Putative uncharacterized protein; Product inferred by homology to UniProt.
    
 
 0.483
CDA21894.1
dNA polymerase I; Product inferred by homology to UniProt.
   
 
 0.477
CDA22758.1
uDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Product inferred by homology to UniProt.
    
  0.458
CDA22448.1
ybgI/family dinuclear metal center protein; Product inferred by homology to UniProt; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
     
 0.456
CDA22475.1
Putative uncharacterized protein; Product inferred by homology to UniProt.
       0.440
hisB
Imidazoleglycerol-phosphate dehydratase; Product inferred by homology to UniProt; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
   
 
 0.435
CDA22476.1
Uncharacterized protein; Product inferred by homology to UniProt.
       0.420
CDA22477.1
alpha-L-rhamnosidase N-terminal domain protein; Product inferred by homology to UniProt.
       0.420
Your Current Organism:
Bacteroides sp. CAG144
NCBI taxonomy Id: 1262736
Other names: B. sp. CAG:144, Bacteroides sp. CAG:144
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