STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDB19818.1Stage IV sporulation protein A; Product inferred by homology to UniProt. (490 aa)    
Predicted Functional Partners:
CDB21044.1
Stage III sporulation protein AA; Product inferred by homology to UniProt.
  
  
 0.909
CDB21227.1
Sporulation transcriptional regulator SpoIIID; Product inferred by homology to UniProt.
  
  
 0.890
CDB21041.1
Putative uncharacterized protein; Product inferred by homology to UniProt.
  
    0.883
CDB20777.1
Putative uncharacterized protein; Product inferred by homology to UniProt.
  
  
 0.875
CDB21088.1
Putative uncharacterized protein; Product inferred by homology to UniProt.
  
   
 0.860
CDB21038.1
Putative uncharacterized protein; Product inferred by homology to UniProt.
  
  
 0.854
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.846
CDB19898.1
Stage II sporulation protein; Product inferred by homology to UniProt; Belongs to the anti-sigma-factor antagonist family.
  
   
 0.844
CDB20084.1
Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.843
gpr
Germination protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
   
 0.843
Your Current Organism:
Blautia sp. CAG52
NCBI taxonomy Id: 1262758
Other names: B. sp. CAG:52, Blautia sp. CAG:52
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.