STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfpPhosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (411 aa)    
Predicted Functional Partners:
CDE28677.1
Pyruvate kinase; Product inferred by homology to UniProt; Belongs to the pyruvate kinase family.
 
 0.987
CDE27686.1
Fructose-1 6-bisphosphate aldolase class II; Product inferred by homology to UniProt.
  
 
 0.900
pfkA-2
6-phosphofructokinase 2; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
  
0.875
pgi
Glucose-6-phosphate isomerase; Product inferred by homology to UniProt; Belongs to the GPI family.
  
 0.874
CDE27050.1
1-phosphofructokinase; Product inferred by homology to UniProt; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
     
 0.872
CDE28864.1
Kinase PfkB family; Product inferred by homology to UniProt.
  
 
 0.866
CDE27790.1
Transketolase; Product inferred by homology to UniProt; Belongs to the transketolase family.
  
 
 0.780
CDE27989.1
Transketolase; Product inferred by homology to UniProt; Belongs to the transketolase family.
  
 
 0.780
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.773
guaA
gMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
   
  
 0.759
Your Current Organism:
Catenibacterium sp. CAG290
NCBI taxonomy Id: 1262767
Other names: C. sp. CAG:290, Catenibacterium sp. CAG:290
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