node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDE27128.1 | CDE27447.1 | BN591_00123 | BN591_01694 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hypoxanthine phosphoribosyltransferase; Product inferred by homology to UniProt; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.871 |
CDE27128.1 | CDE27954.1 | BN591_00123 | BN591_00377 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Uncharacterized protein; Product inferred by homology to UniProt. | 0.494 |
CDE27128.1 | CDE28136.1 | BN591_00123 | BN591_00042 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Inosine 5-monophosphate dehydrogenase; Product inferred by homology to UniProt. | 0.925 |
CDE27128.1 | CDE28939.1 | BN591_00123 | BN591_01281 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | aICARFT/IMPCHase bienzyme; Product inferred by homology to UniProt. | 0.494 |
CDE27128.1 | guaA | BN591_00123 | BN591_01011 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | gMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.966 |
CDE27128.1 | purA | BN591_00123 | BN591_01012 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.732 |
CDE27128.1 | purH | BN591_00123 | BN591_00369 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Bifunctional purine biosynthesis protein PurH; Product inferred by homology to UniProt. | 0.494 |
CDE27447.1 | CDE27128.1 | BN591_01694 | BN591_00123 | Hypoxanthine phosphoribosyltransferase; Product inferred by homology to UniProt; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.871 |
CDE27447.1 | CDE27954.1 | BN591_01694 | BN591_00377 | Hypoxanthine phosphoribosyltransferase; Product inferred by homology to UniProt; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Uncharacterized protein; Product inferred by homology to UniProt. | 0.514 |
CDE27447.1 | CDE28136.1 | BN591_01694 | BN591_00042 | Hypoxanthine phosphoribosyltransferase; Product inferred by homology to UniProt; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Inosine 5-monophosphate dehydrogenase; Product inferred by homology to UniProt. | 0.906 |
CDE27447.1 | CDE28939.1 | BN591_01694 | BN591_01281 | Hypoxanthine phosphoribosyltransferase; Product inferred by homology to UniProt; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | aICARFT/IMPCHase bienzyme; Product inferred by homology to UniProt. | 0.848 |
CDE27447.1 | guaA | BN591_01694 | BN591_01011 | Hypoxanthine phosphoribosyltransferase; Product inferred by homology to UniProt; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | gMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.956 |
CDE27447.1 | purA | BN591_01694 | BN591_01012 | Hypoxanthine phosphoribosyltransferase; Product inferred by homology to UniProt; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.918 |
CDE27447.1 | purH | BN591_01694 | BN591_00369 | Hypoxanthine phosphoribosyltransferase; Product inferred by homology to UniProt; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Bifunctional purine biosynthesis protein PurH; Product inferred by homology to UniProt. | 0.848 |
CDE27953.1 | CDE27954.1 | BN591_00376 | BN591_00377 | Lactaldehyde reductase; Product inferred by homology to UniProt. | Uncharacterized protein; Product inferred by homology to UniProt. | 0.481 |
CDE27954.1 | CDE27128.1 | BN591_00377 | BN591_00123 | Uncharacterized protein; Product inferred by homology to UniProt. | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.494 |
CDE27954.1 | CDE27447.1 | BN591_00377 | BN591_01694 | Uncharacterized protein; Product inferred by homology to UniProt. | Hypoxanthine phosphoribosyltransferase; Product inferred by homology to UniProt; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.514 |
CDE27954.1 | CDE27953.1 | BN591_00377 | BN591_00376 | Uncharacterized protein; Product inferred by homology to UniProt. | Lactaldehyde reductase; Product inferred by homology to UniProt. | 0.481 |
CDE27954.1 | CDE28136.1 | BN591_00377 | BN591_00042 | Uncharacterized protein; Product inferred by homology to UniProt. | Inosine 5-monophosphate dehydrogenase; Product inferred by homology to UniProt. | 0.600 |
CDE27954.1 | CDE28939.1 | BN591_00377 | BN591_01281 | Uncharacterized protein; Product inferred by homology to UniProt. | aICARFT/IMPCHase bienzyme; Product inferred by homology to UniProt. | 0.589 |